
GLP-1s are a tool, not a lifestyle. We use them to help you lose weight faster and safer while we fix the metabolic root cause underneath. The goal is results you keep after you stop the medication, not a prescription you are on forever.
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Sound Familiar?
You meal-prep on Sundays, hit the gym four days a week, and step on the scale Monday morning to see the same number you saw six months ago. The problem is not what you are eating. It is that elevated insulin is telling your body to store fat, sluggish thyroid is slowing your burn rate, or high cortisol is packing it around your midsection. Until someone tests those, no diet will work.
If you're experiencing any of these, we can help.



The Med Matrix Process
Your path to feeling like yourself again, step by step.
Talk with our patient coordinator to discuss your goals, symptoms, and concerns. We will help you understand your options and create a personalized next step, or point you in the best direction.
We run a comprehensive panel of 80+ lab markers along with a full body composition scan so nothing gets missed and your provider has the complete picture.
Our providers review your labs, medical history, and health questionnaires to build a personalized treatment plan tailored to your specific results and goals.
Sit down with your provider for a full hour to go over your results and build a personalized plan using the best of natural and modern medicine.
We continue monitoring your labs, adjusting your plan, and providing support to make sure you see real, measurable progress with your health.
The Difference
Diet Programs & Med Spas typically lack all of the above.
Your Treatment Options
A GLP-1 prescription alone is not a weight loss plan. It is one tool in a protocol that must also address the hormonal, metabolic, and nutritional factors that caused the weight gain in the first place. Without fixing the root cause, the weight comes back when you stop the medication.
Semaglutide is a GLP-1 receptor agonist that slows gastric emptying, increases satiety signals to the brain, and reduces dopamine-driven food cravings. It is effective for weight loss, but studies show that up to two-thirds of patients regain weight after stopping without metabolic support. We use semaglutide as part of a complete protocol, not as a standalone prescription.
Tirzepatide is a dual GIP/GLP-1 receptor agonist with stronger weight loss outcomes and fewer gastrointestinal side effects than semaglutide. It also shows significant anti-inflammatory benefits. At Med Matrix, we evaluate which medication fits your metabolic profile based on labs, not guesswork.
Low testosterone in men and women, thyroid dysfunction, and elevated cortisol all sabotage blood sugar control and make weight loss nearly impossible regardless of diet. We test and optimize these hormones alongside your GLP-1 protocol so your metabolism has the hormonal foundation it needs to actually respond to treatment.
On a GLP-1, your appetite drops significantly. If you eat a 200-calorie salad because you are not hungry, you lose muscle instead of fat. We build a protein-forward nutrition plan and resistance training protocol that preserves lean muscle mass while the GLP-1 targets fat. Studies show up to 40% of weight lost on GLP-1s can be muscle without proper training and nutrition.
Expert Care
Our providers bring together board-certified medicine, functional medicine, and specialized expertise so your plan is built on real data, not guesswork.

MD
Board-Certified Internal Medicine

ND, LAc
Naturopathic Doctor & Acupuncturist

PA-C, MMSc, IFMCP
Functional Medicine Provider

MPAS, PA-C
Physician Assistant

DC, DNM, MS, PA-C, FAAMFM, ABAAHP
Functional & Regenerative Medicine

DNP, ANP-BC
Adult Nurse Practitioner

Aesthetics Director & Co-founder
Patient Stories
Don't just take our word for it. Watch real patients share their experiences with Med Matrix.

Gained weight from 5 years at a desk job. Semaglutide plus a 12-week workout program. Big results. Food noise eliminated.

Lost 30 lbs with Med Matrix, 50 total. People say she looks younger. Decreased body fat, better skin, more energy.

Lost 37 lbs in 8 months on tirzepatide. Was nearly pre-diabetic. Brain fog gone. Energy up.

Lost 50 lbs in one year at age 65. Off three prescription medications. No more high blood pressure or high cholesterol.

Lost weight as part of her hormone and functional medicine protocol. Sleeping better, understanding the biology behind why the weight was there.

Functional medicine and TRT transformed his body composition. Calls the experience life changing.
Learn More

See exactly what to expect during your initial consultation, from check-in to personalized treatment plan.

Understand why our approach to weight loss goes deeper than what typical clinics offer.
The Med Matrix Podcast
Our providers break down the science behind your health concerns and what you can do about them.

Dr. Rose explores how GLP-1 medications are reshaping metabolic health beyond just the scale.

The metabolic, hormonal, and gut factors that make weight loss nearly impossible without the right support.

Evidence-based biohacking strategies for sustainable fat loss and energy optimization.

How your gut microbiome influences estrogen metabolism, body composition, and stubborn belly fat.
More Patient Reviews
“I had tried every diet and program out there. Med Matrix ran tests my other doctors never ordered and found hormonal and metabolic issues that were keeping the weight on. I have lost 42 pounds and kept it off for over a year.”
“The GLP-1 medication combined with their metabolic support made all the difference. I finally stopped fighting my body and started working with it. Down 35 pounds and my energy is through the roof.”
“I was skeptical because nothing had ever worked long-term. But this was different. They tested everything, explained why I was stuck, and built a plan that actually made sense for my body. I feel like a different person.”
Visit Us
Conveniently located off the Maine Mall Road, serving patients across Maine & New Hampshire.



198 Maine Mall Rd
South Portland, ME 04106
Mon - Fri: 8:00 AM - 5:00 PM
By appointment only
Common Questions
Semaglutide and tirzepatide are the two most common. Your provider reviews your lab results, medical history, and goals, then recommends the one most likely to work for your metabolic profile. If the first option is not the right fit, we adjust.
Most patients lose 15 to 20 percent of their body weight over 6 to 12 months. But the real difference is that we treat the metabolic cause, not just appetite, so the weight stays off. Patients who only take GLP-1s without metabolic support regain two-thirds of the weight within a year of stopping. Our patients do not, because the underlying problem is fixed.
No. We will not prescribe a GLP-1 until we have your lab results. If your fasting insulin is normal and your thyroid is fine, a GLP-1 might not even be the right first step. The medication is one tool inside a larger protocol that includes hormone optimization, gut health support, nutrient repletion, and lifestyle guidance.
Fasting insulin, full thyroid panel (TSH, free T3, free T4, thyroid antibodies), morning cortisol, estradiol, testosterone, DHEA-S, inflammatory markers like hs-CRP, and key nutrients like vitamin D, B12, and ferritin. These markers tell us exactly where your metabolism is breaking down.
The most common are mild nausea and reduced appetite in the first two to four weeks. These almost always fade as your body adjusts. We start at a low dose and increase slowly. If side effects persist, we adjust the protocol rather than push through.
That is the whole point of testing and treating the root cause. If we correct your insulin resistance, optimize your thyroid, and rebalance your hormones while you are on the medication, your body can maintain the new weight without it. We build an exit plan into every protocol.
We give you nutrition guidance based on your lab results. If you are insulin resistant, we will steer you toward lower-glycemic eating. If your cortisol is high, we address meal timing and stress-related eating patterns. There is no generic meal plan. The food recommendations come from your bloodwork.
Every 4 to 6 weeks during active weight loss. Each visit includes a progress review and, when needed, updated labs to make sure the protocol is working. Telehealth is available for follow-ups if you cannot make it in person.
Yes, and in many cases those conditions are the reason the weight will not come off. We treat thyroid dysfunction and hormonal conditions like PCOS as part of the weight loss protocol, not as separate problems. Fixing those often unlocks weight loss that was previously impossible.
Telehealth apps prescribe the medication without testing your metabolism first. That is like prescribing glasses without an eye exam. At Med Matrix, we run full metabolic bloodwork, identify the specific hormonal and metabolic issues keeping the weight on, build a protocol around those findings, and monitor your labs throughout treatment. The medication alone is not the solution. The testing and the protocol around it are what make the results last.
Med Matrix is a precision and functional medicine clinic that helps patients find and address the root cause of their health concerns. We use advanced testing, personalized treatment plans, and innovative therapies to improve energy, hormones, recovery, body composition, performance, and long-term health.
Med Matrix looks deeper than symptom management. Instead of simply treating surface-level issues, we use advanced diagnostics and personalized care plans to uncover what is really going on and create a strategy to help you feel and perform at your best.
Med Matrix is for adults who want to improve their health, fix ongoing symptoms, optimize hormones, lose weight, improve recovery, increase energy, enhance performance, and stay healthier as they age.
No. Med Matrix does not take insurance.
Yes. Many Med Matrix services can be paid for using HSA or FSA funds.
Yes. Med Matrix offers payment plan options.
The cost depends on your goals, the testing you need, and the treatments included in your personalized plan. Our team will walk you through pricing based on exactly what is right for you.
The first step is scheduling an initial consultation or discovery call. From there, we guide you through testing, provider review, and your personalized treatment plan.
Yes. Med Matrix offers telehealth for consultations, follow-ups, and lab reviews when appropriate.
Yes. Med Matrix provides detailed receipts and documentation that patients can use for HSA, FSA, or possible out-of-network reimbursement purposes.
Take the First Step
Take our free 2-minute quiz and find out if medical weight loss is right for you.